Dr. Mark A. McIntosh serves as the vice chancellor of research, graduate studies and economic development for the University of Missouri and as the vice president for research and economic development for the UM System.
Dr. McIntosh received his bachelor’s degree in biology from Knox College in Galesburg, IL. He earned a doctorate in microbiology from the University of Texas-Austin in 1978, and served as a postdoctoral fellow in biochemistry from 1978 to 1981 at the University of California-Berkeley.
Dr. McIntosh began his MU career in 1981 as an assistant professor of microbiology with a specialization in bacterial genetics and genomics. He went on to serve for 15 years as chair of the MU Department of Molecular Microbiology and Immunology. Dr. McIntosh was the first director of the DNA Core Facility at MU, and in 2004 was named director of all MU core facilities, a position that involved oversight of seven additional campus technology centers: mass spectrometry, NMR spectroscopy, electron and light microscopy, protein crystallization and x-ray diffraction, flow cytometry, and transgenic animal production. In 2008, he led a team that initiated the MU Informatics Research Core, a facility aimed at enhancing campus infrastructure and technical expertise in specific bioinformatics subdisciplines, among them genomics, proteomics and metabolomics.
His scientific background includes significant expertise in basic research involving bacterial genetics/genomics. More recent work has focused on the investigation of the role of iron-binding small molecules in the inflammatory response to adherent-invasive Escherichia coli (AIEC) in inflammatory bowel disease, and the linkage between iron-controlled virulence factors and the expression of two-partner contact-dependent inhibition (CDI) systems in the lung pathogenesis of Pseudomonas aeruginosa. In addition, Dr. McIntosh has directed a program-project grant in collaboration with USDA to develop new diagnostic and therapeutic targets for detection and control of foreign animal diseases, including mycoplasmas and pestiviruses. This project involved three primary laboratories at MU and collaborating laboratories at the Plum Island Animal Disease Center in New York.
Over the course of his career, Dr. McIntosh has successfully garnered extramural support from NSF, NIH, USDA, Cystic Fibrosis Association of Missouri and the Missouri Life Sciences Research Board, as well as industry sponsors.View All Members